基因名：
HMBS
产品别名：
PBG-D； PBGD； PORC； UPS； HMBS； hydroxymethylbilane synthase； hydroxymethylbilane synthase； porphobilinogen deaminase； porphyria, acute; Chester type； pre-uroporphyrinogen synthase； uroporphyrinogen I synthase； uroporphyrinogen I synthetase； 卟胆原脱氨酶； 羟甲基胆素合酶(HMBS)；
背景信息：
Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including hemoglobin. Defects in PBGD are the cause of acute intermittent porphyria.
