基因名:
CFHR2
产品别名:
CFHL2; FHR2; HFL3; CFHR2; complement factor H related 2; complement factor H related 2; complement factor H-related protein 2; DDESK59; FHR-2; H factor (complement)-like 3; factor H-related gene 2; h factor-like 3; h factor-like protein 2; 补体因子H相关蛋白2;
背景信息:
Complement Factor H-Related Protein 2 (CFHR2) is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 is synthesized as a 270 amino acid precursor that contains an 18 amino acid signal peptide and a 252 amino acid mature chain with 4 Sushi (CCP/SCR) domains. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.