基因名:
HDAC1
产品别名:
GON-10; HD1; KDAC1; RPD3; RPD3L1; HDAC1; histone deacetylase 1; histone deacetylase 1; histone deacetylase 1; protein deacetylase HDAC1; protein decrotonylase HDAC1; reduced potassium dependency, yeast homolog-like 1; 磷酸化组蛋白去乙酰化酶1; 组蛋白去乙酰化酶1; 组蛋白脱乙酰基酶1(HDAC1);
背景信息:
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]