基因名：
GTF2F2
产品别名：
BTF4； RAP30； TF2F2； TFIIF； GTF2F2； general transcription factor IIF subunit 2； general transcription factor IIF subunit 2； general transcription factor IIF subunit 2； ATP-dependent helicase GTF2F2； TFIIF-beta； general transcription factor IIF 30 kDa subunit； general transcription factor IIF, polypeptide 2, 30kDa； transcription initiation factor IIF subunit beta； transcription initiation factor RAP30； 通用转录因子IIF亚基2/TFIIF RAP 30；
背景信息：
Transcription initiation factor IIF subunit beta; In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. TFIIF, a heteromer composed of a small (RAP 30) and a large (RAP 74) subunit, is required for RNA polymerase II to assemble into a preinitiation complex formed by promotor DNA and the general factors TFIID, IIA and IIB. In addition, TFIIF stimulates transcription elongation by RNA polymerase II.
