基因名:
GTF2B
产品别名:
TF2B; TFIIB; GTF2B; general transcription factor IIB; general transcription factor IIB; transcription initiation factor IIB; RNA polymerase II transcription factor IIB; S300-II; general transcription factor TFIIB; 通用转录因子GTF2B;
背景信息:
Transcription Initiation Factor IIB (TFIIB) is an essential factor for transcription by RNA Polymerase II. TFIIB localizes to the nucleus where it forms a complex (the DAB complex) with transcription factor IID and IIA. TFIIB plays a role as a bridge between IID, which initially recognizes the promoter sequence, and RNA polymerase II. TFIIB is involved in the selection of transcription start site.