基因名：
GSTZ1
产品别名：
GSTZ1-1； MAAI； MAAID； MAI； GSTZ1； glutathione S-transferase zeta 1； glutathione S-transferase zeta 1； maleylacetoacetate isomerase； S-(hydroxyalkyl)glutathione lyase； glutathione S-alkyltransferase； glutathione S-aralkyltransferase； glutathione S-aryltransferase； glutathione transferase zeta 1； maleylacetone isomerase； 谷胱甘肽S转移酶ζ1；
背景信息：
Maleylacetoacetate Isomerase (MAAI) belongs to the Glutathione S-Transferase super-family. MAAI encodes multifunctional enzymes in the detoxification of electrophilic molecules by conjugation with glutathione, for example, mutagens, carcinogens and several therapeutic drugs. MAAI is a bifunctional protein with low glutathione peroxidase activity with T-butyl and cumene hydroperoxides. MAAI can catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid. But it has minimal glutathione-conjugating activity with 7-chloro-4-nitrobenz-2-oxa-1, ethacrynic acid 3-diazole and maleylacetoacetate isomerase activity.
