基因名:
GRIN2B
产品别名:
DEE27; EIEE27; GluN2B; MRD6; NMDAR2B; NR2B; NR3; hNR3; GRIN2B; glutamate ionotropic receptor NMDA type subunit 2B; glutamate ionotropic receptor NMDA type subunit 2B; glutamate receptor ionotropic, NMDA 2B; GluN2B(alt_5'UTR); N-methyl D-aspartate receptor subtype 2B; N-methyl-D-aspartate receptor subunit 3; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; N-甲基-D-天氡氨酸离子能谷氨酸受体2B(GRIN2B); 磷酸化谷氨酸受体2B; 谷氨酸受体2B; 谷氨酸受体NMDAζ2;
背景信息:
N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008].