基因名:
GLI1
产品别名:
GLI; PAPA8; PPD1; GLI1; GLI family zinc finger 1; GLI family zinc finger 1; zinc finger protein GLI1; GLI-Kruppel family member GLI1; glioma-associated oncogene 1; glioma-associated oncogene homolog 1 (zinc finger protein); oncogene GLI; GLI家族锌指蛋白1(GLI1); 磷酸化脑胶质瘤相关蛋白; 脑胶质瘤相关蛋白(锌指蛋白5);
背景信息:
This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]