基因名:
FN1
产品别名:
CIG; ED-B; FINC; FN; FNZ; GFND; GFND2; LETS; MSF; SMDCF; FN1; fibronectin 1; fibronectin 1; fibronectin; cold-insoluble globulin; epididymis secretory sperm binding protein; migration-stimulating factor; 纤维连接蛋白; 纤维连接蛋白/Ugl-Y3; 纤连蛋白(FN); 纤连蛋白(FN)天然蛋白; 纤连蛋白(FN)真核蛋白;
背景信息:
Fibronectin1(FN1) is a secreted protein and contains 12 fibronectin type-I domains,fibronectin type-II domains and 16 fibronectin type-III domains.Recombinant human fibronectin fragment, is a protein of 63 kDa containing a central cell-binding domain, a high affinity heparin-binding domain II,and CS1 site within the alternatively spliced III CS region of human fibronectin. Cells bind to a VLA-4 ligand, a CS-I site, and a VLA-5 ligand, a cell attachment domain, and virus vectors binds to a heparin binding domain II, which co-locates the cell and the virus vector on NovoNectin. This process enhances the density of both cells and vectors, and facilitates the gene transduction in the result.