基因名:
FMO5
产品别名:
hBVMO1; FMO5; flavin containing dimethylaniline monoxygenase 5; flavin containing dimethylaniline monoxygenase 5; flavin-containing monooxygenase 5; FMO 5; NADPH oxidase; NAPDH oxidase; baeyer-Villiger monooxygenase 1; dimethylaniline monooxygenase [N-oxide-forming] 5; dimethylaniline oxidase 5; flavin containing monooxygenase 5; hepatic flavin-containing monooxygenase 5; 二甲基苯胺单加氧酶5;
背景信息:
The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. Localizing to microsomal and endoplasmic reticulum membranes, FMO5 (flavin containing monooxygenase 5), also known as dimethylaniline monooxygenase [N-oxide-forming] 5, hepatic flavin-containing monooxygenase 5 or dimethylaniline oxidase 5, is a 533 amino acid protein belonging to the FMO family. Expressed in adult and fetal liver, FMO5 is unlike other FMO family members because it does not function as a drug-metabolizing enzyme. FMO5 binds FAD as a cofactor and is encoded by a gene located on human chromosome 1q21.1.