基因名:
FKBP2
产品别名:
FKBP-13; FKBP13; PPIase; FKBP2; FKBP prolyl isomerase 2; FKBP prolyl isomerase 2; peptidyl-prolyl cis-trans isomerase FKBP2; 13 kDa FK506-binding protein; 13 kDa FKBP; FK506 binding protein 2, 13kDa; FK506-binding protein 2; PPIase FKBP2; epididymis secretory sperm binding protein; immunophilin FKBP13; proline isomerase; rapamycin-binding protein; rotamase; FK506结合蛋白2(FKBP2);
背景信息:
Peptidyl-prolyl cis-trans isomerase FKBP2(FKBP2 for short), also named 13 kDa FK506-binding protein, FK506-binding protein 2, Immunophilin FKBP13, Rotamase, is a endoplasmic reticulum peripheral membrane protein. It contains 1 PPIase FKBP-type domain and belongs to the FKBP-type PPIase family, FKBP2 subfamily which takes part in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP2 is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. FKBP2 functions as an ER chaperone and as a component of membrane cytoskeletal scaffolds.