基因名：
FAU
产品别名：
FAU1； Fub1； Fubi； MNSFbeta； RPS30； S30； asr1； FAU； FAU ubiquitin like and ribosomal protein S30 fusion； FAU ubiquitin like and ribosomal protein S30 fusion； FAU ubiquitin-like and ribosomal protein S30； 40S ribosomal protein S30； FAU-encoded ubiquitin-like protein； FBR-MuSV-associated ubiquitously expressed； Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)； monoclonal nonspecific suppressor factor beta； ribosomal protein S30； small ribosomal subunit protein eS30； ubiquitin-like protein fubi and ribosomal protein S30； ubiquitin-like-S30 fusion protein； 泛素样核糖体蛋白S30/MNSF-β；
背景信息：
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. A wide range of enzymes facilitate in the proteolytic Ub pathway, including monoclonal nonspecific suppressor factor-beta (MNSF-beta), a subunit of MNSF, which is a lymphokine product of a murine T cell hybrid-oma that restricts the production of LPS-induced immunoglobulin secreting cells in an antigen-nonspecific manner. MNSF-beta is a ubiquitin-like fusion protein consisting of the ribosomal protein S30 and a protein that shares 36% sequence identity with ubiquitin. This ubiquitin-like segment (Ubi-L) can be cleaved from MNSF-beta in the cytosol.
