基因名:
FASN
产品别名:
FAS; OA-519; SDR27X1; FASN; fatty acid synthase; fatty acid synthase; fatty acid synthase; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase; 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-[acyl-carrier-protein] synthase; Acyl-[acyl-carrier-protein] hydrolase; Enoyl-[acyl-carrier-protein] reductase; [Acyl-carrier-protein] S-acetyltransferase; [Acyl-carrier-protein] S-malonyltransferase; short chain dehydrogenase/reductase family 27X, member 1; type I fatty acid synthase; 脂肪酸合成酶; 脂肪酸合成酶蛋白; 脂肪酸合酶(FASN);
背景信息:
FASN (Fatty Acid Synthase) is a central enzyme in de novo lipogenesis. FAS is a target for SREBP and is upregulated by LXR activation; it is also one of the accepted markers for insulin resistance, SREBP and LXR activation.