基因名:
F7
产品别名:
SPCA; F7; coagulation factor VII; coagulation factor VII; coagulation factor VII; FVII coagulation protein; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; proconvertin; 凝血因子7; 凝血因子VII; 凝血因子Ⅶ(F7);
背景信息:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.