基因名:
EEF1D
产品别名:
EF-1D; EF1D; FP1047; EEF1D; eukaryotic translation elongation factor 1 delta; eukaryotic translation elongation factor 1 delta; elongation factor 1-delta; EF-1-delta; antigen NY-CO-4; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); 延伸因子EF-1δ; 真核翻译延伸因子1δ(EEF1d);
背景信息:
This gene encodes a subunit of the elongation factor-1complex, which is responsible for the enzymatic delivery ofaminoacyl tRNAs to the ribosome. This subunit, delta, functions asguanine nucleotide exchange factor. It is reported that followingHIV-1 infection, this subunit interacts with HIV-1 Tat. Thisinteraction results in repression of translation of host cellproteins and enhanced translation of viral proteins. Severalalternatively spliced transcript variants encoding multipleisoforms have been found for this gene. Related pseudogenes havebeen defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided byRefSeq, Aug 2010].