基因名:
EDNRA
产品别名:
ET-A; ETA; ETA-R; ETAR; ETRA; MFDA; hET-AR; EDNRA; endothelin receptor type A; endothelin receptor type A; endothelin-1 receptor; G protein-coupled receptor; endothelin receptor subtype A; endothelin-1-specific receptor; 内皮素受体A; 内皮素受体A(ETRA);
背景信息:
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]