基因名:
DTX1
产品别名:
RNF140; hDx-1; DTX1; deltex E3 ubiquitin ligase 1; deltex E3 ubiquitin ligase 1; E3 ubiquitin-protein ligase DTX1; RING-type E3 ubiquitin transferase DTX1; deltex 1, E3 ubiquitin ligase; deltex homolog 1; protein deltex-1; Deltex同源物1(DTX1); E3泛素蛋白连接酶DTX1;
背景信息:
Deltex is a RING finger ubiquitin ligase which is conserved from Drosophila to Humans and is a regulator of Notch signaling pathway. Deltex regulates both B-cell lineage and splenic marginal-zone B-cell commitment. Deltex is implicated in neurogenesis, lymphogenesis and myogenesis as well as marginal zone B cell differentiation.