基因名：
DOK1
产品别名：
P62DOK； pp62； DOK1； docking protein 1； docking protein 1； docking protein 1； Downstream of tyrosine kinase 1； D酪氨酸激酶衰减蛋白1； 停靠蛋白1(DOK1)； 磷酸化D酪氨酸激酶衰减蛋白1；
背景信息：
Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
