基因名:
DNMT3A
产品别名:
DNMT3A2; HESJAS; M.HsaIIIA; TBRS; DNMT3A; DNA methyltransferase 3 alpha; DNA methyltransferase 3 alpha; DNA (cytosine-5)-methyltransferase 3A; DNA (cytosine-5-)-methyltransferase 3 alpha; DNA MTase HsaIIIA; DNA cytosine methyltransferase 3A2; cysteine methyltransferase DNMT3A; DNA甲基转移酶-3α; DNA甲基转移酶3A(DNMT3A); 磷酸化DNA甲基转移酶-3α;
背景信息:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]