基因名：
NQO1
产品别名：
DHQU； DIA4； DTD； NMOR1； NMORI； QR1； NQO1； NAD(P)H quinone dehydrogenase 1； NAD(P)H quinone dehydrogenase 1； NAD(P)H dehydrogenase [quinone] 1； DT-diaphorase； NAD(P)H dehydrogenase, quinone 1； NAD(P)H:Quinone acceptor oxidoreductase type 1； NAD(P)H:menadione oxidoreductase 1； NAD(P)H:quinone oxidoreductase 1； NAD(P)H:quinone oxireductase； azoreductase； diaphorase (NADH/NADPH) (cytochrome b-5 reductase)； diaphorase-4； dioxin-inducible 1； menadione reductase； phylloquinone reductase； quinone reductase 1； 醌NADH脱氢酶1(NQO1)； 醌氧化还原酶； 醌氧化还原酶蛋白；
背景信息：
This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].
