重组细胞色素P450 2C19蛋白

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重组细胞色素P450 2C19蛋白

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant CYP2C19
Recombinant cytochrome P450 family 2 subfamily C member 19 protein

基因名：

CYP2C19

产品别名：

CPCJ； CYP2C； CYPIIC17； CYPIIC19； P450C2C； P450IIC19； CYP2C19； cytochrome P450 family 2 subfamily C member 19； cytochrome P450 family 2 subfamily C member 19； cytochrome P450 2C19； (R)-limonene 6-monooxygenase； (S)-limonene 6-monooxygenase； (S)-limonene 7-monooxygenase； S-mephenytoin 4-hydroxylase； cytochrome P-450 II C； cytochrome P450, family 2, subfamily C, polypeptide 19； cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19； cytochrome P450-11A； cytochrome P450-254C； fenbendazole monooxygenase (4'-hydroxylating)； flavoprotein-linked monooxygenase； mephenytoin 4'-hydroxylase； mephenytoin 4-hydroxylase； microsomal monooxygenase； xenobiotic monooxygenase；细胞色素P450 2C19；

背景信息：

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq]