基因名：
CYP1A2
产品别名：
CP12； CYPIA2； P3-450； P450(PA)； CYP1A2； cytochrome P450 family 1 subfamily A member 2； cytochrome P450 family 1 subfamily A member 2； cytochrome P450 1A2； P450 form 4； aryl hydrocarbon hydroxylase； cholesterol 25-hydroxylase； cytochrome P(3)450； cytochrome P450 4； cytochrome P450, family 1, subfamily A, polypeptide 2； cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2； cytochrome P450-P3； dioxin-inducible P3-450； flavoprotein-linked monooxygenase； hydroperoxy icosatetraenoate dehydratase； microsomal monooxygenase； xenobiotic monooxygenase； 细胞色素P450家族成员1A2(CYP1A2)；
背景信息：
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu region. [provided by RefSeq].sequences flanked by direct repeats in the 3' untranslated.
