基因名：
CXADR
产品别名：
CAR； CAR4/6； HCAR； CXADR； CXADR Ig-like cell adhesion molecule； CXADR Ig-like cell adhesion molecule； coxsackievirus and adenovirus receptor； 46 kD coxsackievirus and adenovirus receptor (CAR) protein； CVB3-binding protein； HCVADR； coxsackie virus and adenovirus receptor； coxsackievirus B-adenovirus receptor； 柯萨奇病毒腺病毒受体(CXADR)；
背景信息：
Coxsackievirus and Adenovirus Receptor (CAR) belongs to the CTX family of the Ig superfamily. CXADR is a type I transmembrane glycoprotein and expressed in pancreas, brain, heart, small intestine, testis, prostate. It is a receptor that mediates gene transfer and also act as an adhesion molecule within junctional complexes, notably between epithelial cells lining body cavities and within myocardial intercalated discs. CXADR contains an extracellular domain, a transmembrane helix and a C-terminal intracellular domain. The C-terminal interacts with few cytoplasmic junctional proteins, microtubules and the actin cytoskeleton.
