基因名：
CCN2
产品别名：
CTGF； HCS24； IGFBP8； NOV2； CCN2； cellular communication network factor 2； cellular communication network factor 2； CCN family member 2； IBP-8； IGF-binding protein 8； IGFBP-8； connective tissue growth factor； hypertrophic chondrocyte-specific protein 24； insulin-like growth factor-binding protein 8； CTGF/CCN2蛋白； 结缔组织生长因子； 结缔组织生长因子(CTGF)；
背景信息：
CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family, which is comprised of six secreted proteins that reside in the extracellular matrix (ECM). CTGF causes a variety of cellular responses including reduced cell adhesion and enhanced cell migration and proliferation. CTGF has also been shown to be essential for epithelial to mesenchymal transition (EMT), a process whereby normal functioning cells morph into ones that produce mainly scar tissue (of which collagen in the major protein component).
