基因名:
SLC25A10
产品别名:
DIC; MTDPS19; SLC25A10; solute carrier family 25 member 10; solute carrier family 25 member 10; mitochondrial dicarboxylate carrier; dicarboxylate ion carrier; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10; 二羧酸转运蛋白(DIC); 线粒体二羧酸载体蛋白;
背景信息:
The mitochondrial dicarboxylate carrier protein (mDIC) belongs to superfamily of mitochondrial transporters. It has been demonstrated that the expression of mDIC leads to hyperpolarization of the mitochondria, as well as succinate uptake by the mitochondria. It is highly expressed in adipose tissue, where its expression is downregulated by insulin and upregulated by free fatty acids. mDIC is also thought to play a role in glyceroneogenesis.