基因名：
CSRP2
产品别名：
CRP2； LMO5； SmLIM； CSRP2； cysteine and glycine rich protein 2； cysteine and glycine rich protein 2； cysteine and glycine-rich protein 2； LIM domain only 5, smooth muscle； LIM domain only protein 5； LMO-5； cysteine-rich protein 2； epididymis secretory sperm binding protein； smooth muscle cell LIM protein； 富含半胱氨酸蛋白2；
背景信息：
CRP2 is a 193 amino acid nuclear protein that belongs to the CRP family of LIM domain proteins. Highly expressed in smooth muscle of aorta, CRP2 is thought to have a role in embryonic vascular system development and is downregulated following cell injury or PDGF-B exposure. CRP2 contains two LIM zinc-binding domains and is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
