基因名:
CSNK1D
产品别名:
ASPS; CKI-delta; CKId; CKIdelta; FASPS2; HCKID; CSNK1D; casein kinase 1 delta; casein kinase 1 delta; casein kinase I isoform delta; casein kinase I; tau-protein kinase CSNK1D; 酪蛋白激酶1δ(CSNK1d); 酪蛋白激酶δ1;
背景信息:
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Central component of the circadian clock. May act as a negative regulator of circadian rhythmicity by phosphorylating PER1 and PER2. Retains PER1 in the cytoplasm.
Tissue specificity: Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. In blood, highly expressed in hemopoietic cells and mature granulocytes. Also found in monocytes and lymphocytes.