基因名:
CRP
产品别名:
PTX1; CRP; C-reactive protein; C-reactive protein; C-reactive protein; C-reactive protein, pentraxin-related; pentraxin 1; C-反应蛋白; C反应蛋白; C反应蛋白(CRP); C反应蛋白(CRP)天然蛋白; C反应蛋白(CRP)真核蛋白; 腺苷受体蛋白;
背景信息:
Pentraxins are plasma proteins characterized by their pentameric discoid assembly and their Ca2+ dependent ligand binding, such as Serum amyloid P component (SAP) and C-reactive Protein (CRP), which are cytokine-inducible acute-phase proteins implicated in innate immunity. CRP binds to ligands containing phosphocholine, SAP binds to amyloid fibrils, DNA, chromatin, fibronectin, C4-binding proteins and glycosaminoglycans. "Long" pentraxins have N-terminal extensions to the common pentraxin domain; one group, the neuronal pentraxins, may be involved in synapse formation and remodeling, and they may also be able to form heteromultimers.