基因名：
CPN1
产品别名：
CPN； SCPN； CPN1； carboxypeptidase N subunit 1； carboxypeptidase N subunit 1； carboxypeptidase N catalytic chain； anaphylatoxin inactivator； arginine carboxypeptidase； carboxypeptidase K； carboxypeptidase N catalytic subunit； carboxypeptidase N polypeptide 1 50 kD； carboxypeptidase N small subunit； carboxypeptidase N, polypeptide 1； kininase I； kininase-1； lysine carboxypeptidase； plasma carboxypeptidase B； serum carboxypeptidase N； 激肽酶1； 羧肽酶N1(CPN1)；
背景信息：
Carboxypeptidase N is a plasma metallo-protease that cleaves basic amino acids from the C terminal of peptides and proteins. The enzyme is important in the regulation of peptides like kinins and anaphylatoxins, and has also been known as kininase-1 and anaphylatoxin inactivator. This enzyme is a tetramer comprised of two identical regulatory subunits and two identical catalytic subunits; this gene encodes the catalytic subunit. Mutations in this gene can be associated with angioedema or chronic urticaria resulting from carboxypeptidase N deficiency. [provided by RefSeq, Jul 2008]
