基因名：
ACKR2
产品别名：
CCBP2； CCR10； CCR9； CMKBR9； D6； hD6； ACKR2； atypical chemokine receptor 2； atypical chemokine receptor 2； atypical chemokine receptor 2； C-C chemokine receptor D6； CC-chemokine-binding receptor JAB61； chemokine (C-C motif) receptor 9； chemokine (C-C) receptor 9； chemokine receptor CCR-10； chemokine receptor CCR-9； chemokine receptor D6； chemokine-binding protein 2； chemokine-binding protein D6； 趋化因子受体D6； 趋化因子结合蛋白2；
背景信息：
Chemokine Receptor D6 is a member of the C-C (β chemokine) G protein-coupled receptor family. This family is characterized by a pair of adjacent cysteine residues. C-C chemokine receptor family members also include CKR-1, CKR-2A, CKR-2B, CKR-3, CKR-4, CKR-5, CKR-6, CKR-7, CKR-8, CKR-9, CKR-10, CCXCKR, Bonzo, BOB (brother of Bonzo) and Duffy blood group antigen. Each of these receptors are G protein-coupled, seven pass transmembrane domain proteins whose major physiological role is to function in the chemotaxis of T cells and phagocytic cells to sites of inflammation. Chemokine Receptor D6 acts as a receptor for various C-C type chemokines, including SCYA2/MCP-1, SCY3/MIP-1-α, SCYA5/RANTES and SCYA7/MCP-3. It is expressed primarily in placental tissues and fetal liver, but is also detected in lymphatic endothelial cells, lymph nodes and mucosa of the small and large intestines.
