基因名:
CCR7
产品别名:
BLR2; CC-CKR-7; CCR-7; CD197; CDw197; CMKBR7; EBI1; CCR7; C-C motif chemokine receptor 7; C-C motif chemokine receptor 7; C-C chemokine receptor type 7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; EBV-induced G protein-coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; MIP-3 beta receptor; chemokine (C-C motif) receptor 7; lymphocyte-specific G protein-coupled peptide receptor; 细胞表面趋化因子受体7; 趋化因子C-C-基元受体7(CCR7);
背景信息:
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. [provided by RefSeq, Jul 2008]