基因名:
CCR4
产品别名:
CC-CKR-4; CD194; CKR4; CMKBR4; ChemR13; HGCN:14099; K5-5; CCR4; C-C motif chemokine receptor 4; C-C motif chemokine receptor 4; C-C chemokine receptor type 4; C-C CKR-4; CCR-4; chemokine (C-C motif) receptor 4; chemokine (C-C) receptor 4; 细胞表面趋化因子受体4; 趋化因子C-C-基元受体4(CCR4);
背景信息:
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]