基因名：
TPP1
产品别名：
CLN2； GIG1； LPIC； SCAR7； TPP-1； TPP1； tripeptidyl peptidase 1； tripeptidyl peptidase 1； tripeptidyl-peptidase 1； cell growth-inhibiting gene 1 protein； growth-inhibiting protein 1； lysosomal pepstatin insensitive protease； lysosomal pepstatin-insensitive carboxypeptidase； tripeptidyl aminopeptidase； tripeptidyl peptidase I； 三肽基肽酶Ⅰ(TPP1)； 细胞生长抑制基因1蛋白；
背景信息：
Tripeptidyl-Peptidase 1 (TPP1) belongs to the peptidase S53 family. TPP1 is detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues. TPP1 is lysosomal serine protease with tripeptidyl-peptidase I activity. TPP1 may act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. TPP1 requires substrates with an unsubstituted N-terminus. TPP1 mutations have also been shown to cause neuronal ceroid lipofuscinosis type 2 (CLN2).
