基因名：
TBCB
产品别名：
CG22； CKAP1； CKAPI； TBCB； tubulin folding cofactor B； tubulin folding cofactor B； tubulin-folding cofactor B； cytoskeleton associated protein 1； cytoskeleton-associated protein CKAPI； tubulin-specific chaperone B； 微管蛋白折叠辅酶B(TBCB)； 细胞骨架相关蛋白1/微管蛋白折叠辅助因子B；
背景信息：
Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.
