基因名：
CENPE
产品别名：
CENP-E； KIF10； MCPH13； PPP1R61； CENPE； centromere protein E； centromere protein E； centromere-associated protein E； Centromere autoantigen E (312kD)； centromere protein E, 312kDa； kinesin family member 10； kinesin-7； kinesin-related protein CENPE； protein phosphatase 1, regulatory subunit 61； 着丝粒相关蛋白E； 着丝粒蛋白E(CENPE)；
背景信息：
Centrosome-associated protein E (CENPE) is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. This protein is required for stable spindle microtubule capture at kinetochores which is a necessary step in chromosome alignment during prometaphase. This protein also couples chromosome position to microtubule depolymerizing activity. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. [provided by RefSeq, Nov 2014]
