基因名：
CENPA
产品别名：
CENP-A； CenH3； CENPA； centromere protein A； centromere protein A； histone H3-like centromeric protein A； centromere autoantigen A； centromere protein A, 17kDa； centromere-specific histone； 磷酸化着丝粒蛋白A；
背景信息：
Centromeres are the differentiated chromosomal domains that specify the mitotic behavior of chromosomes. CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere. CENPA is proposed to be a component of a modified nucleosome or nucleosome-like structure in which it replaces 1 or both copies of conventional histone H3 in the (H3-H4)2 tetrameric core of the nucleosome particle. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].
