基因名:
CALCA
产品别名:
CALC1; CGRP; CGRP-I; CGRP-alpha; CGRP1; CT; KC; PCT; CALCA; calcitonin related polypeptide alpha; calcitonin related polypeptide alpha; calcitonin; calcitonin gene-related peptide 1; alpha-type CGRP; calcitonin 1; calcitonin gene-related peptide I; calcitonin/calcitonin-related polypeptide, alpha; katacalcin; 降钙素; 降钙素(CT); 降钙素(CT)合成多肽; 降钙素原蛋白; 降钙素基因相关肽(CGRP); 降钙素基因相关肽1; 降钙素基因相关肽1/2; 鲑鱼降钙素/降钙素;
背景信息:
Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+), opposing the effects of parathyroid hormone (PTH). Its importance in humans has not been as well established as its importance in other animals, as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.