基因名：
CA4
产品别名：
CAIV； Car4； RP17； CA4； carbonic anhydrase 4； carbonic anhydrase 4； carbonic anhydrase 4； CA-IV； carbonate dehydratase IV； carbonic anhydrase IV； carbonic dehydratase IV； 碳酸酐酶4； 碳酸酐酶Ⅳ(CA4)；
背景信息：
Carbonic Anhydrase 4 (CA4) belongs to the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Carbonic anhydrase 4 is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Carbonic anhydrase 4 may stimulate the sodium/bicarbonate transporter activity of SLC4A4 that acts in pH homeostasis. It may have a role in inherited renal abnormalities of bicarbonate transport. Furthermore, Carbonic anhydrase 4 is essential for acid overload removal from the retina and retina epithelium and acid release in the choriocapillaris.
