基因名:
CA1
产品别名:
CA-I; CAB; Car1; HEL-S-11; CA1; carbonic anhydrase 1; carbonic anhydrase 1; carbonic anhydrase 1; carbonate dehydratase I; carbonic anhydrase B; carbonic anhydrase I; cyanamide hydratase CA1; epididymis secretory protein Li 11; epididymis secretory sperm binding protein; 碳酸酐酶1; 碳酸酐酶Ⅰ(CA1);
背景信息:
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonamide derivatives and coumarins. In addition, CA1 is a zinc metalloenzyme that has reversible hydration of carbon dioxide. It can hydrate cyanamide to urea.