基因名:
BIK
产品别名:
BIP1; BP4; NBK; BIK; BCL2 interacting killer; BCL2 interacting killer; bcl-2-interacting killer; BCL2-interacting killer (apoptosis-inducing); apoptosis inducer NBK; apoptosis-inducing NBK; natural born killer; 促凋亡Bik蛋白; 磷酸化促凋亡Bik蛋白;
背景信息:
The protein encoded by this gene is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.