基因名：
BAX
产品别名：
BCL2L4； BAX； BCL2 associated X, apoptosis regulator； BCL2 associated X, apoptosis regulator； apoptosis regulator BAX； BCL2 associated X protein； BCL2-associated X protein omega； Baxdelta2G9； Baxdelta2G9omega； Baxdelta2omega； bcl-2-like protein 4； bcl2-L-4； Bax蛋白； Bcl2关联X蛋白(Bax)； BCL2相关X蛋白； 磷酸化Bax；
背景信息：
Apoptosis Regulator BAX (BAX) belongs to the Bcl-2 family. BAX exists as a homodimer and is expressed in a wide variety of tissues. The Bax gene encodes different isoforms including Bax alpha (21 kDa) and Bax beta (24 kDa). Although both isoforms contain BH1, BH2 and BH3 domains, Bax beta has a unique carboxyl terminus and does not contain a hydrophobic transmembrane domain. BAX accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. BAX also promotes activation of CASP3, and thereby apoptosis.
