基因名：
ATP1B1
产品别名：
ATP1B； ATP1B1； ATPase Na+/K+ transporting subunit beta 1； ATPase Na+/K+ transporting subunit beta 1； sodium/potassium-transporting ATPase subunit beta-1； ATPase, Na+/K+ transporting, beta 1 polypeptide； Beta 1-subunit of Na(+),K(+)-ATPase； Na, K-ATPase beta-1 polypeptide； adenosinetriphosphatase； sodium pump subunit beta-1； sodium-potassium ATPase subunit beta 1 (non-catalytic)； sodium/potassium-dependent ATPase beta-1 subunit； sodium/potassium-transporting ATPase beta-1 chain； 钠/钾离子转运ATP酶β1肽(ATP1b1)； 钠钾ATP酶蛋白b1；
背景信息：
The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
