基因名：
ATM
产品别名：
AT1； ATA； ATC； ATD； ATDC； ATE； TEL1； TELO1； ATM； ATM serine/threonine kinase； ATM serine/threonine kinase； serine-protein kinase ATM； A-T mutated； AT mutated； TEL1, telomere maintenance 1, homolog； ataxia telangiectasia mutated； serine/threonine kinase ATM； 毛细血管扩张性共济失调症突变蛋白； 毛细血管扩张性共济失调突变因子(ATM)； 磷酸化毛细血管扩张性共济失调症突变蛋白；
背景信息：
ATM is a 370 kDa nuclear phosphoprotein involved in the autosomal recessive disease Ataxia Telangiectasia (AT). ATM belongs to a novel family of proteins associated with cell cycle regulation, apoptosis, and response to DNA damage repair (DNA damage caused by such things as ionizing irradiation activates ATM kinase). The C terminal region has extensive homology to the catalytic domains of Phosphatidylinositol 3 kinases (PI3 kinases).
