基因名:
ASGR1
产品别名:
ASGPR; ASGPR1; CLEC4H1; HL-1; ASGR1; asialoglycoprotein receptor 1; asialoglycoprotein receptor 1; asialoglycoprotein receptor 1; C-type lectin domain family 4 member H1; hepatic lectin H1; 去唾液酸糖蛋白受体1(ASGR1); 唾液酸糖蛋白受体1;
背景信息:
Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor, belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits, ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins, recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1, results in the complex is internalized and transported to a sorting organelle, then ASGPR1 and ligand can be disassociated, ASGPR1 returns to the cell membrane surface.