重组芳香烃受体核转录蛋白样1

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重组芳香烃受体核转录蛋白样1

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

Recombinant BMAL1
Recombinant basic helix-loop-helix ARNT like 1 protein

基因名：

BMAL1

产品别名：

ARNTL； ARNTL1； BMAL1c； JAP3； MOP3； PASD3； TIC； bHLHe5； BMAL1； basic helix-loop-helix ARNT like 1； basic helix-loop-helix ARNT like 1； aryl hydrocarbon receptor nuclear translocator-like protein 1； ARNT-like protein 1, brain and muscle； PAS domain containing 3； PAS domain-containing protein 3； aryl hydrocarbon receptor nuclear translocator like； bHLH-PAS protein JAP3； basic helix-loop-helix family member e5； basic-helix-loop-helix-PAS orphan MOP3； basic-helix-loop-helix-PAS protein MOP3； brain and muscle ARNT-like 1； class E basic helix-loop-helix protein 5； member of PAS protein 3； member of PAS superfamily 3； testis tissue sperm-binding protein Li 50e；芳香烃受体核转录蛋白样1；

背景信息：

Component of the circadian clock oscillator which includes the CRY proteins, CLOCK or NPAS2, ARNTL or ARNTL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Efficient DNA binding requires dimerization with another bHLH protein. Heterodimerization with CLOCK is required for E-box-dependent transactivation, for CLOCK nuclear translocation and degradation, and, for phosphorylation of both CLOCK and ARNTL. Interaction with PER and CRY proteins requires translocation to the nucleus. Interaction of the CLOCK-ARNTL heterodimer with PER or CRY inhibits transcription activation. Interacts with HSP90; with AHR in vitro, but not in vivo.