基因名：
RHOC
产品别名：
ARH9； ARHC； H9； RHOH9； RHOC； ras homolog family member C； ras homolog family member C； rho-related GTP-binding protein RhoC； RAS-related homolog 9； epididymis secretory sperm binding protein； oncogene RHO H9； ras homolog gene family, member C； rho cDNA clone 9； rhoC GTPase； small GTP binding protein RhoC；
背景信息：
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
