基因名:
APLP1
产品别名:
APLP; APLP1; amyloid beta precursor like protein 1; amyloid beta precursor like protein 1; amyloid beta precursor like protein 1; amyloid beta (A4) precursor-like protein 1; amyloid precursor-like protein 1; amyloid-like protein 1; 淀粉样蛋白β前体样蛋白1; 淀粉样蛋白β前体样蛋白1(APLP1);
背景信息:
Amyloid-like protein 1 (APLP-1) is a member of the highly conserved amyloid precursor protein gene family. APLP1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. APLP1, together with APLP2, are important modulators of glucose. APLP1 may also play a role in synaptic maturation during cortical development, and is genetically linked to Alzheimer'sdisease.