基因名:
ANXA3
产品别名:
ANX3; ANXA3; annexin A3; annexin A3; annexin A3; 35-alpha calcimedin; Annexin III (lipocortin III); PAP-III; annexin III (lipocortin III, 1,2-cyclic-inositol-phosphate phosphodiesterase, placental anticoagulant protein III, calcimedin 35-alpha); annexin-3; calcimedin 35-alpha; inositol 1,2-cyclic phosphate 2-phosphohydrolase; lipocortin III; placental anticoagulant protein III; 膜粘连蛋白A3; 膜联蛋白A3(ANXA3);
背景信息:
Annexin A3(ANXA3)contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. ANXA3 is Inhibitor of phospholipase A2 and cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. it also also play a role in anti-coagulant properties.