基因名:
ALOX12
产品别名:
12-LOX; 12S-LOX; LOG12; ALOX12; arachidonate 12-lipoxygenase, 12S type; arachidonate 12-lipoxygenase, 12S type; polyunsaturated fatty acid lipoxygenase ALOX12; 12S-lipoxygenase; Arachidonate 12-lipoxygenase, 12S-type; arachidonate (12S)-lipoxygenase; arachidonate (15S)-lipoxygenase; arachidonate 15-lipoxygenase,15S-type; linoleate 13S-lipoxygenase; lipoxin synthase 12-LO; platelet 12-LOX; platelet-type 12-lipoxygenase; platelet-type lipoxygenase 12; 12脂氧合酶; 花生四烯酸-12-脂加氧酶(ALOX12);
背景信息:
This gene encodes a member of the lipoxygenase family of proteins. The encoded enzyme acts on different polyunsaturated fatty acid substrates to generate bioactive lipid mediators including eicosanoids and lipoxins. The encoded enzyme and its reaction products have been shown to regulate platelet function. Elevated expression of this gene has been observed in pancreatic islets derived from human diabetes patients. Allelic variants in this gene may be associated with susceptibility to toxoplasmosis. Multiple pseudogenes of this gene have been identified in the human genome. [provided by RefSeq, Aug 2017]