基因名:
AGT
产品别名:
ANHU; SERPINA8; hFLT1; AGT; angiotensinogen; angiotensinogen; angiotensinogen; alpha-1 antiproteinase, antitrypsin; angiotensin I; angiotensin II; fetal-liver predominant transporter 1; pre-angiotensinogen; serine (or cysteine) proteinase inhibitor; serpin A8; serpin peptidase inhibitor, clade A, member 8; 血管紧张素III; 血管紧张素Ⅱ(AngII)合成多肽; 血管紧张素原; 血管紧张素原(AGT); 血管紧张素原(AGT)真核蛋白;
背景信息:
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in the encoding gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.